Senescence-Associated Pro-inflammatory Cytokines and Tumor Cell Plasticity

Unbalanced Pro-Inflammatory and Anti-Inflammatory Cytokines Ratio and Endometriosis: A Contributive Pathogenic Role?

Progressive Insight into Tumor Promotion with Pro-inflammatory Cytokines

IL-1β on mouse skin [2,3]; The study of tumor promotion by both okadaic acid and TPA revealed that TNF-α is an essential tumor promoter in TNF-α-deficient mouse skin initiated with DMBA [3]; Inhibitors of PP1 and PP2A induced tumor promotion on mouse skin, in rat glandular stomach and rat liver initiated with carcinogens [4]; TNF-α, IL-1α and IL-1β induced clonal growth of v-Ha-ras-transfected ...

Pro-inflammatory cytokines affect pancreatic carcinoma cell. Endothelial cell interactions.

OBJECTIVES The potential role of surgery-induced pro-inflammatory cytokines on the development of tumor recurrence in pancreatic cancer was investigated. MAIN OUTCOME MEASURES The adhesion of 3 human pancreatic carcinoma cell lines, PanC1, MiaPaCa and BxPC3 to monolayers of microvascular endothelial cells after pre-incubation with 0.1 or 10 ng/mL IL-1beta, TNF-alpha or IL-6 was assessed in a ...

Pro-inflammatory cytokines in atherosclerosis.

Pro-inflammatory cytokines and adipose tissue.

Cytokines appear to be major regulators of adipose tissue metabolism. Therapeutic modulation of cytokine systems offers the possibility of major changes in adipose tissue behaviour. Cytokines within adipose tissue originate from adipocyte, preadipocyte and other cell types. mRNA expression studies show that adipocytes can synthesise both tumour necrosis factor alpha (TNF-alpha) and several inte...